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Occlusafe

Occlusafe

Occlusive Micro Balloon Catheter

Product Overview

Microballoon Interventions a Technical Revolution in Transarterial Embolization

Terumo Interventional Oncology Division presents Occlusafe, an occlusive micro-balloon.

Through Pressure Gradient Effect, Occlusafe as micro-balloon catheter, offers the ability to redistribute blood flow and access the microcirculation, leading to an increased accumulation of therapeutics into the target lesion with minimal off-target embolization. This may be associated with improved clinical outcomes in challenging lesions3

Features and Benefits

Large Lesions Challenges:

Large lesions partially respond to current TACE treatment due to a poor uptake of embolic. Multiple or combined treatments are required to reach a complete response.

Flow Distribution

Through Pressure Gradient Effect, Balloon Occlusion with Occlusafe offers the ability to redistribute blood flow and access the microvascular circulation, leading to an increased accumulation of therapeutics into the target lesion with minimal off-target embolization.

Access to Microvascular Circulation

Balloon Occlusion with Occlusafe allows a better visualization for improved diagnosis and higher uptake of embolic into the target lesion. 1

Excellence in Navigability

Terumo excellence in lesion access technology guarantees for a superb precision and accuracy in navigation through complex vessel anatomies.

Expected Benefits from Micro Balloon Embolization (MBE)

・Greater tumor or radiological response3
・Improved clinical outcome4-6
・Better diagnosis thanks to more visibility1
・Full protection against reflux7

Standard balloon inflation for complete occlusion

Inflate balloon 1.1 or 1.2 times bigger size to the vessel
diameter. Maximal diameter is 4 mm. Maximal volume is 0.10 ml.

Item Specifications

Balloon Catheter O.D Cathter length Compatible GW Compatible catheter
minimum lumen size
Max size Length Injection
volume
Distal Proximal
4.0mm 10mm 0.1mm 0.90mm
(2.7fr)
0.94mm
(2.8fr)
150cm 0.014”/
0.36mm
0.040”/
1.02mm
Balloon Max size 4.0mm
Length 10mm
Injection volume 0.1mm
Catheter
O.D
Distal 0.90mm
(2.7fr)
Proximal 0.94mm
(2.8fr)
Cathter length 150cm
Compatible GW0.014”/
0.36mm
Compatible catheter
minimum lumen size
0.040”/
1.02mm

Reference

Note. Comparison is done between TACE performed with Occlusafe micro-balloon catheter and TACE with a standard micro-catheter.

  • 1. Irie Toshiyuki (2013): Dense accumulation of lipiodol emulsion in hepatocellular carcinoma nodule during selective balloon-occluded transarterial chemoembolization: measurementof balloon occlude arterial stump pressure. Cardiovasc Intervent Radiol. DOI: 10.1001/s00270-012-0476-z
  • 2. Terumitsu Hasebe; Minimally Invasive Therapy & Allied Technologies. 2015 Apr;24(2):94-100. doi: 10.3109/13645706.2014.951657. Epub 2014 Sep 29. PubMed.
  • 3. Hriotaka Arai: Hepatology Research (2015): Safety and efficacy of balloon-occluded trancatheter arterial chemoembolization using miriplatin for hepatocellular carcinoma; 45. 663-666
  • 4. Takayasu K, Muramatsu Y, Maeda T, Iwata R, Furukawa H, Muramatsu Y, Moriyama N, Okusaka T, Okada S, Ueno H. Targeted transarterial oily chemoembolization for small foci of hepatocellular carcinoma using a unified helical CT and angiography system: analysis of factors affecting local recurrence and survival rates. AJR Am J Roentgenol 2001; 176: 681-688 [PMID: 11222205 DOI: 10.2214/ajr.176.3.1760681]
  • 5. Hayashi K, Ina H, Tezuka M, Okada Y, Irie T. Local therapeutic results of computed tomography-guided transcatheter arterial chemoembolization for hepatocellular carcinoma: results of 265 tumors in 79 patients. Cardiovasc Intervent Radiol 2007; 30: 1144-1155 [PMID: 17909884 DOI: 10.1007/s00270-007-9169-4]
  • 6. Hatanaka T, Arai H, Shibasaki M, Tojima H, Takizawa D, Toyoda M, Takayama H, Abe T, Sato K, Kakizaki S, Yamada M. Factors predicting overall response and overall survival in hepatocellular carcinoma patients undergoing balloon-occluded transcatheter arterial chemoembolization: A retrospective cohort study. Hepatol Res 2018; 48: 165-175 [PMID: 28500686 DOI: 10.1111/hepr.12912] Data on files. Reference OS-003. Terumo Europe NV.

Customer Support

At TERUMO, we don't just deliver quality medical products, we offer the resources and necessary support for them to be used to their full potential. Contact us for any assistance you may need.